IN VITRO AND IN VIVO ANTIVIRUS ACTIVITY OF AN ANTI-PROGRAMMED DEATH-LIGAND 1 (PD-L1) RAT-BOVINE CHIMERIC ANTIBODY AGAINST BOVINE LEUKEMIA VIRUS INFECTION.

Programmed death-1 (PD-1), an immunoinhibitory receptor on T cells, is known to be involved in immune evasion through its binding to PD-ligand 1 (PD-L1) in many chronic diseases.We previously found that PD-L1 expression was upregulated in cattle infected with bovine leukemia virus (BLV) and that an antibody that blocked the PD-1/PD-L1 interaction r

This paper examines how the evolution of architectural generative design processes aim to apply similar physical and geometrical principles of biological processes taking place during development and to translate them to fabrication processes.In analogy to the reaction-diffusion mechanism for biological pattern prediction, the logic of stripe is us

Advances in sugarcane breeding have contributed significantly to improvements in agronomic traits and crop yield.However, the growing global demand for sugar and biofuel in the context of climate change requires further improvements in cane and sugar yields.Attempts to achieve the desired rates of genetic gain in sugarcane by conventional breeding

The main theme of this article is the frequent lack of adequate and effective public dialogue and participation within the schemes of the contemporary urban planning practices referred as neoliberal hegemony of urbanization (Brenner and Theodore, 2005, Miles, 2004, Fezer, 2010).On the other side we can Straight Mounted Brush observe artists-led cul

Human spaceflight is associated with several health-related issues as a result of long-term exposure to microgravity, ionizing radiation, and higher levels of psychological stress.Frequent reported skin problems in space include rashes, itches, and a delayed wound healing.Access to space is restricted by financial and logistical issues; as a conseq